Both of the polishes consist of a dense silver glitter with blue and pink glitter particles mixed in. I applied two coats of each polish plus a top coat for the swatches. Formula and application were the same, no issues with either polish.
Here they are side by side:
Index and Ring Fingers: Nicole by OPI Look at Me, Look at Me
Middle and Pinkie Fingers: Dr.'s Remedy Serene Silver Glitter
I cannot tell the difference between the two polishes in photos or in person. They are both gorgeous and very sparkly. It is funny though how two companies can interpret the same color and come up with different names. Nicole by OPI with a high energy name of "Look at Me, Look at Me," while Dr.'s remedy is such a peaceful one of "Serene." Wouldn't you expect completely different polishes with such names?
Here is a closeup of the bottles. As always, you can click on any of the photos to zoom in...
Nicole by OPI: Available at Target $7.04, Big 3 Free (Free of Formaldehyde, Toluene and DBP)
Dr.'s Remedy: Available online at remedynails.com $17, Big 3 Free (Free of Formaldehyde, Toluene and DBP). Doctor formulated to contain Tea Tree Oil, Vitamins and Wheat Protein for better nail health and fungus control.
Hope you found this comparison useful!
Let me know if you would like to see more in the future :)
Thanks for looking!